IL29 Protein (AA 21-200, partial) (His-SUMO Tag)
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- 抗原 See all IL29 蛋白
- IL29 (Interleukin 29 (IL29))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-200, partial
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This IL29 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- VPTSKPTTTG KGCHIGRFKS LSPQELASFK KARDALEESL KLKNWSCSSP VFPGNWDLRL LQVRERPVAL EAELALTLKV LEAAAGPALE DVLDQPLHTL HHILSQLQAC IQPQPTAGPR PRGRLHHWLH RLQEAPKKES AGCLEASVTF NLFRLLTRDL KYVADGNLCL RTSTHPEST-
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product IL29 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- IL29 (Interleukin 29 (IL29))
- 别名
- IFNL1 (IL29 产品)
- 别名
- IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
- 背景
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- 分子量
- 35.85 kDa
- UniProt
- Q8IU54
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