Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
RGD1562346 Protein, AV127319 Protein, H2b-613 Protein, T25626 Protein, DKFZp469C0528 Protein, H2b Protein, GL105 Protein, H2B Protein, H2B.1 Protein, H2BFQ Protein, H2BGL105 Protein, H2BQ Protein, histone cluster 2 H2B family member E Protein, histone cluster 2, H2be Protein, histone cluster 1, H2bl Protein, histone cluster 2 H2B family member e Protein, histone H2B Protein, Hist2h2be Protein, HIST2H2BE Protein, Hist1h2bl Protein, H2B Protein
背景
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.