Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
抗原
ID1
(Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))
ID1 Protein, id6 Protein, cb108 Protein, wu:fb57e11 Protein, AI323524 Protein, D2Wsu140e Protein, Idb1 Protein, bHLHb24 Protein, ID125A Protein, ID Protein, inhibitor of DNA binding 1 Protein, inhibitor of DNA binding 1, HLH protein Protein, id1 Protein, ID1 Protein, Id1 Protein
背景
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer .