Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
抗原
DNTTIP1
(Deoxynucleotidyltransferase, Terminal, Interacting Protein 1 (DNTTIP1))
MGC79023 Protein, DNTTIP1 Protein, TDIF1 Protein, DKFZp469H0914 Protein, C20orf167 Protein, Tdif1 Protein, dJ447F3.4 Protein, 6430706C13Rik Protein, deoxynucleotidyltransferase terminal interacting protein 1 Protein, deoxynucleotidyltransferase, terminal, interacting protein 1 L homeolog Protein, deoxynucleotidyltransferase, terminal, interacting protein 1 Protein, DNTTIP1 Protein, dnttip1.L Protein, dnttip1 Protein, Dnttip1 Protein
背景
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) . Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes, may recruit HDAC1 complexes to nucleosomes or naked DNA.