LRRC32 Protein (partial) (Fc Tag)
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- 抗原 See all LRRC32 蛋白
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- partial
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LRRC32 protein is labelled with Fc Tag.
- 应用范围
- Western Blotting (WB), ELISA
- 序列
- His 20 - Asn 627
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Biological Activity Comment
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Measured by its binding ability in a functional ELISA. Immobilized Latent TGFB1, N-His at 5 μg/mL (100 uL/well) can bind Human LRRC32, Fc Tag with a linear range of 0.039-2.5 μg/mL (QC tested).
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- Discover our top product LRRC32 蛋白
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- 应用备注
- This recombinant protein can be used for E, WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- 抗原
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 别名
- LRRC32 (LRRC32 产品)
- 别名
- D11S833E Protein, GARP Protein, AI426318 Protein, D11S833Eh Protein, D7H11S833E Protein, EG434215 Protein, Garp Protein, leucine rich repeat containing 32 Protein, LRRC32 Protein, Lrrc32 Protein
- 背景
- Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
- 分子量
- 92.6 kDa
- 基因ID
- 2615
- 途径
- Activated T Cell Proliferation
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