AZGP1 Protein (AA 21-298)
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- 抗原 See all AZGP1 蛋白
- AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-298
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human full-length zinc-alpha-2-glycoprotein (aa 21-298) is untagged.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product AZGP1 蛋白
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alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 1-298) protein (GST tag)
AZGP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 22-298) protein (GST tag)AZGP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 21-298) protein (His tag)AZGP1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Solid
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
- 别名
- Zinc-alpha-2-glycoprotein (AZGP1 产品)
- 别名
- Zag Protein, ZA2G Protein, ZAG Protein, ZA2GA Protein, Zna2gp Protein, alpha-2-glycoprotein 1, zinc Protein, alpha-2-glycoprotein 1, zinc-binding Protein, Azgp1 Protein, AZGP1 Protein
- 背景
- Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
- 分子量
- ~30kDa
- UniProt
- P25311
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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