Ret Proto-Oncogene Protein (RET) (DYKDDDDK-His Tag)
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- 抗原 See all Ret Proto-Oncogene (RET) 蛋白
- Ret Proto-Oncogene (RET)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Ret Proto-Oncogene protein is labelled with DYKDDDDK-His Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Purified recombinant protein of human ret proto-oncogene (RET), with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag) protein expressed in Human 293HEK cells.
- Produced with end-sequenced ORF clone
- 纯化方法
- Purified
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RET 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 1 x PBS, pH 7.4, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Ret Proto-Oncogene (RET)
- 别名
- ret proto-oncogene (RET 产品)
- 别名
- c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein
- 背景
- This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
- 分子量
- 70.5 kDa
- NCBI登录号
- NP_066124
- 途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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