HMOX2 Protein (full length)
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- 抗原 See all HMOX2 蛋白
- HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))
- 蛋白类型
- Native
- 产品特性
- full length
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宿主
- 大鼠
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资源
- 大鼠
- 应用范围
- SDS-PAGE (SDS), Western Blotting (WB)
- 序列
- MSSEVETSEG VDESENNSTA PEKENHTKMA DLSELLKEGT KEAHDRAENT QFVKDFLKGN IKKELFKLAT TALYFTYSAL EEEMDRNKDH PAFAPLYFPT ELHRKEALIK DMEYFFGENW EEQVKCSEAA QKYVDRIHYV GQNEPELLVA HAYTRYMGDL SGGQVLKKVA QRALKLPSTG EGTQFYLFEH VDNAQQFKQF YRARMNALDL SMKTKERIVE EANKAFEYNM QIFSELDQAG SMLTKETLED GLPVHDGKGD VRKCPFYAAQ PDKGTLGGSN CPFRTAMAVL RKPSLQLILA ASVALVAGLL AWYYM
- 特异性
- ~36 kDa
- 纯化方法
- Ion-exchange Purified
- 纯度
- >90% pure using SDS - PAGE analysis.
- Top Product
- Discover our top product HMOX2 蛋白
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Heme Oxygenase (Decycling) 2 (HMOX2) (AA 1-316) protein (GST tag)
HMOX2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Heme Oxygenase (Decycling) 2 (HMOX2) (AA 1-264) proteinHMOX2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
Heme Oxygenase (Decycling) 2 (HMOX2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)HMOX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heme Oxygenase (Decycling) 2 (HMOX2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HMOX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heme Oxygenase (Decycling) 2 (HMOX2) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)HMOX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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This product has been certified >90% pure using SDS - PAGE analysis.
- 限制
- 仅限研究用
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- 浓度
- Lot specific
- 缓冲液
- 20 mM Tris pH 7.5, 0.1 mM EDTA, 0.25 % Na cholate, <20 mM KCl
- 储存条件
- -80 °C
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- 抗原
- HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))
- 别名
- HO-2 (HMOX2 产品)
- 别名
- HO-2 Protein, HO2 Protein, HMOX2 Protein, Ho-2 Protein, im:6909100 Protein, si:dkey-44g23.7 Protein, AtHO2 Protein, T9J22.22 Protein, T9J22_22 Protein, heme oxygenase 2 Protein, hmox2 Protein, ho-2 Protein, heme oxygenase 2 Protein, Heme oxygenase 2 Protein, heme oxygenase 2, putative Protein, heme oxygenase 2a Protein, heme oxygenase 2 L homeolog Protein, HMOX2 Protein, Hmox2 Protein, HO2 Protein, ho2 Protein, CNF01200 Protein, CPR_0203 Protein, CGB_F5120W Protein, hmox2a Protein, hmox2.L Protein
- 背景
- Heme-oxygenase is a ubiquitous enzyme that catalyzes the initial and rate-limiting steps in heme catabolism yielding equimolar amounts of biliverdin, iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin and the free iron is sequestered to ferritin (1). These products have important physiological effects as carbon monoxide is a potent vasodilator, biliverdin and bilirubin are potent antioxidants, and the free iron increases oxidative stress and regulates the expression of many mRNAs (2). There are three isoforms of heme-oxygenase, HO-1, HO-2 and HO-3, however HO-1 and HO-2 are the major isoforms as they both have been identified in mammals (3). HO-1, also known as heat shock protein 32, is an inducible isoform activated by most oxidative stress inducers, cytokines, inflammatory agents and heat shock. HO-2 is a constitutive isoform which is expressed under homeostatic conditions. HO-1 is also considered to be a cytoprotective factor in that free heme is highly reactive and cytotoxic, and secondly, carbon monoxide is a mediator inhibiting the inflammatory process and bilirubin is a scavenger for reactive oxygen, both of which are the end products of heme catalyzation (4). It has also been shown that HO-1 deficiency may cause reduced stress defense, a pro-inflammatory tendency (5), susceptibility to atherosclerotic lesion formation (6), endothelial cell injury, and growth retardation (7). Up-regulation of HO-1 is therefore said to be one of the major defense mechanisms of oxidative stress (4).
- 基因ID
- 79239
- NCBI登录号
- NP_077363
- UniProt
- P23711
- 途径
- Transition Metal Ion Homeostasis
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