This Poliovirus Receptor protein is labelled with Fc Tag.
应用范围
Functional Studies (Func)
序列
AA 21-343
产品特性
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 62.2 kDa. As a result of glycosylation, The protein migrates as 70-100 kDa under reducing (R) condition and 130-160 kDa under non-reducing (NR) condition on SDS-PAGE gel.
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.