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Pleiotrophin Protein (PTN)

PTN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >96 % as determined by SDS-PAGE and HPLC. Func Active
产品编号 ABIN2830304
发货至: 中国
  • 抗原 See all Pleiotrophin (PTN) 蛋白
    Pleiotrophin (PTN)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    资源
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Functional Studies (Func)
    序列
    GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
    产品特性
    Biological Activity: Fully biologically active when compared to standard. The biological activity was measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre-coated wi
    纯度
    >96 % as determined by SDS-PAGE and HPLC.
    过滤
    0.2 μm filtered
    Top Product
    Discover our top product PTN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    Pleiotrophin (PTN)
    别名
    PTN (PTN 产品)
    别名
    zHBNF Protein, zgc:111787 Protein, harp Protein, hbnf Protein, X-PTF Protein, hbgf8 Protein, negf1 Protein, ptn Protein, PTN Protein, HARP Protein, HBGF8 Protein, HBNF Protein, NEGF1 Protein, PTN-A Protein, HB-GAM Protein, HBBM Protein, HBGF-8 Protein, OSF-1 Protein, HBBN Protein, OSF Protein, Osf-1 Protein, Osf1 Protein, Hbnf Protein, pleiotrophin Protein, pleiotrophin L homeolog Protein, ptn Protein, PTN Protein, ptn.L Protein, Ptn Protein
    背景
    Relevance: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.
    Synonyms: PTN, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule
    分子量
    15.3 kDa
    UniProt
    P21246
    途径
    RTK signaling
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