Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/mL.
Relevance: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. {ECO:0000250|UniProtKB:Q10746, ECO:0000269|PubMed:14764687}. Synonyms: Dendritic cell inflammatory protein 1,