Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/mL, corresponding to a specific activity of > 1.0 x104 IU/mg.
Relevance: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Synonyms: C motif chemokine 1, Lymphotaxin, Small-inducible cytokine C1