PLGF 蛋白
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- 抗原 See all PLGF (PGF) 蛋白
- PLGF (PGF) (Placenta Growth Factor (PGF))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Insect cells (Sf9)
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human PLGF (131aa).
- 纯度
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product PGF 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- PLGF (PGF) (Placenta Growth Factor (PGF))
- 别名
- PLGF (PGF 产品)
- 别名
- D12S1900 Protein, PGFL Protein, PLGF Protein, PlGF-2 Protein, SHGC-10760 Protein, AI854365 Protein, PIGF Protein, Plgf Protein, PlGF Protein, placental growth factor Protein, placenta growth factor Protein, PGF Protein, Pgf Protein, PLGF Protein
- 背景
- Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.
- 分子量
- ~34kDa (dimer)
- UniProt
- P49763
- 途径
- VEGFR1 Specific Signals
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