DLK1 Protein (AA 24-303, Extracellular Domain) (Fc Tag)
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- 抗原 See all DLK1 蛋白
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Extracellular Domain, AA 24-303
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DLK1 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Signal peptide and extracellular domain of human DLK1 (aa 24-303) are fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >90 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLK1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Inhibits adipogenesis of 3T3L-1 cells.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- 别名
- DLK1 (DLK1 产品)
- 别名
- DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, Zog Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 homolog (Drosophila) Protein, delta-like 1 (Drosophila) Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, Dlk1 Protein
- 背景
- The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
- 分子量
- ~65kDa (SDS-PAGE)
- UniProt
- P80370
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