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ZIC2 Protein (ZIC2) (Myc-DYKDDDDK Tag)

ZIC2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735883
发货至: 中国
  • 抗原 See all ZIC2 蛋白
    ZIC2
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    HEK-293 Cells
    标记
    This ZIC2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ZIC2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ZIC2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    ZIC2
    别名
    Zic2 (ZIC2 产品)
    别名
    HPE5 Protein, Ku Protein, cb851 Protein, fb26a03 Protein, wu:fb26a03 Protein, zic2 Protein, zic2.1 Protein, hpe5 Protein, hm:zeh0655 Protein, id:ibd5017 Protein, zic2.2 Protein, zic2l Protein, Zic family member 2 Protein, zinc finger protein of the cerebellum 2 Protein, zic family member 2 (odd-paired homolog, Drosophila), a Protein, Zic family member 2 L homeolog Protein, zic family member 2 (odd-paired homolog, Drosophila) b Protein, ZIC2 Protein, Zic2 Protein, zic2a Protein, zic2.L Protein, zic2b Protein
    背景
    Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos. [UniProtKB/Swiss-Prot Function]
    分子量
    54.8 kDa
    NCBI登录号
    NP_009060
    途径
    Tube Formation
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