JAK3 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all JAK3 蛋白
- JAK3 (Janus Kinase 3 (JAK3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This JAK3 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Tyrosine-protein kinase JAK3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JAK3 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- JAK3 (Janus Kinase 3 (JAK3))
- 别名
- Tyrosine-Protein Kinase Jak3 (JAK3 产品)
- 别名
- JAK-3 Protein, JAK3_HUMAN Protein, JAKL Protein, L-JAK Protein, LJAK Protein, fae Protein, wil Protein, RATJAK3 Protein, JAK Protein, Janus kinase 3 Protein, JAK3 Protein, Jak3 Protein
- 背景
- The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
- 分子量
- 124.9 kDa
- NCBI登录号
- NP_000206
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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