SAA1 Protein (Transcript Variant 1)
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- 抗原 See all SAA1 蛋白
- SAA1 (Serum Amyloid A1 (SAA1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human Serum amyloid A1 (SAA1), transcript variant 1. (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM.* * Schreiber, BM. et al. Biochem J. 1999 Nov 15 344 Pt 1:7-13
- Top Product
- Discover our top product SAA1 蛋白
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Serum Amyloid A1 (SAA1) (AA 1-122) protein (GST tag)
SAA1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Serum Amyloid A1 (SAA1) (AA 1-110), (full length) protein (His tag)SAA1 宿主: 马 宿主: 酵母菌 Recombinant > 90 % ELISA
Serum Amyloid A1 (SAA1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SAA1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Serum Amyloid A1 (SAA1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SAA1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Serum Amyloid A1 (SAA1) (AA 19-129) protein (His tag)SAA1 宿主: 犬 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- 注意事项
- Resuspend the protein in the desired concentration in proper buffer
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- SAA1 (Serum Amyloid A1 (SAA1))
- Abstract
- SAA1 产品
- 别名
- PIG4 Protein, SAA Protein, SAA2 Protein, TP53I4 Protein, zgc:103580 Protein, SAA1 Protein, Saa-1 Protein, Saa2 Protein, serum amyloid A1 Protein, serum amyloid A Protein, amyloid protein A Protein, serum amyloid A protein Protein, serum amyloid a protein Protein, serum amyloid A 1 Protein, serum amyloid protein A Protein, SAA1 Protein, saa Protein, LOC694827 Protein, Sden_2438 Protein, Mmc1_0571 Protein, Riean_0971 Protein, Saa1 Protein, LOC100009168 Protein, LOC101120204 Protein
- 背景
- This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
- 分子量
- 12 kDa
- NCBI登录号
- NP_000322
- 途径
- Toll-Like Receptors Cascades
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