CLEC11A
(C-Type Lectin Domain Family 11, Member A (CLEC11A))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌(E. Coli)
应用范围
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
特异性
Optimal preservation of protein structure, post-translational modifications and functions.
产品特性
Recombinant human SCGF / CLEC11A protein expressed in E. coli.
Produced with end-sequenced ORF clone
Tested for bioactivity.
纯度
> 95 % as determined by SDS-PAGE and Coomassie blue staining
内毒素水平
Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
Biological Activity Comment
Determined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF. ED50 for this effect was observed at 7 ng/ml.
Recombinant human proteins can be used for: Native antigens for optimized antibody production Positive controls in ELISA and other antibody assays Protein-protein interaction In vitro biochemical assays and cell-based functional assays
限制
仅限研究用
缓冲液
Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
注意事项
Resuspend the protein in the desired concentration in proper buffer
储存条件
-80 °C
储存方法
Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
抗原
CLEC11A
(C-Type Lectin Domain Family 11, Member A (CLEC11A))
CLEC11A Protein, CLECSF3 Protein, LSLCL Protein, P47 Protein, SCGF Protein, AW457320 Protein, Clecsf3 Protein, Scgf Protein, C-type lectin domain containing 11A Protein, C-type lectin domain family 11, member a Protein, CLEC11A Protein, Clec11a Protein
背景
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.