RAD51 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- 抗原 See all RAD51 蛋白
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This RAD51 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human RAD51 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD51 蛋白
-
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
- 别名
- Rad51 (RAD51 产品)
- 别名
- BRCC5 Protein, HRAD51 Protein, HsRad51 Protein, HsT16930 Protein, MRMV2 Protein, RAD51A Protein, RECA Protein, CRAD51 Protein, wu:fb38e12 Protein, zgc:77754 Protein, RGD1563603 Protein, ATRAD51 Protein, F22D1.20 Protein, F22D1_20 Protein, RAS associated with diabetes protein 51 Protein, AV304093 Protein, Rad51a Protein, Reca Protein, brcc5 Protein, rad51 Protein, rad51a Protein, reca Protein, xrad51 Protein, RAD51 recombinase Protein, RAS associated with diabetes protein 51 Protein, RAD51 recombinase L homeolog Protein, RAD51 Protein, rad51 Protein, Rad51 Protein, rad51.L Protein
- 背景
- The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 36.8 kDa
- NCBI登录号
- NP_002866
- 途径
- DNA Damage Repair
-