PSMB8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all PSMB8 蛋白
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PSMB8 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PSMB8 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PSMB8 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
- 别名
- Psmb8 (PSMB8 产品)
- 别名
- ALDD Protein, D6S216 Protein, D6S216E Protein, JMP Protein, LMP7 Protein, NKJO Protein, PSMB5i Protein, RING10 Protein, ATP6V0D2 Protein, lmp7 Protein, prosome Protein, macropain Protein, Lmp-7 Protein, Lmp7 Protein, Ring10 Protein, proteasome subunit beta 8 Protein, proteasome subunit beta 8A Protein, proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) Protein, PSMB8 Protein, psmb8a Protein, Psmb8 Protein
- 背景
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified both isoforms are processed to yield the same mature subunit.
- 分子量
- 30.2 kDa
- NCBI登录号
- NP_683720
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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