POGLUT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all POGLUT1 蛋白
- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This POGLUT1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human POGLUT1 / KTELC1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
- 别名
- Poglut1,ktelc1 (POGLUT1 产品)
- 别名
- C3orf9 Protein, CLP46 Protein, KDELCL1 Protein, KTELC1 Protein, MDSRP Protein, Rumi Protein, hCLP46 Protein, MDS010 Protein, 9630046K23Rik Protein, Ktelc1 Protein, protein O-glucosyltransferase 1 Protein, POGLUT1 Protein, Poglut1 Protein
- 背景
- This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
- 分子量
- 46 kDa
- NCBI登录号
- NP_689518
- 途径
- Notch Signaling
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