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PAK4 Protein (Transcript Variant 1)

PAK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
产品编号 ABIN2728177
发货至: 中国
  • 抗原 See all PAK4 蛋白
    PAK4 (P21-Activated Kinase 4 (PAK4))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    Transcript Variant 1
    宿主
    • 11
    • 2
    资源
    • 6
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human PAK4 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 5,595 pmoles/min/μg, according to the Zlyte assay protocol
    Top Product
    Discover our top product PAK4 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PAK4 (P21-Activated Kinase 4 (PAK4))
    别名
    Pak4 (PAK4 产品)
    别名
    5730488L07Rik Protein, AW555722 Protein, mKIAA1142 Protein, im:5916170 Protein, wu:fd12b01 Protein, zgc:92014 Protein, p21 (RAC1) activated kinase 4 Protein, p21 protein (Cdc42/Rac)-activated kinase 4 Protein, PAK4 Protein, Pak4 Protein, pak4 Protein
    背景
    PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    分子量
    33.3 kDa
    NCBI登录号
    NP_005875
    途径
    RTK signaling
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