OCT4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all OCT4 (POU5F1) 蛋白
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This OCT4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human OCT3/4 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product POU5F1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." in: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
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Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." in: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
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- 抗原
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- 别名
- Oct3/4 (POU5F1 产品)
- 别名
- OCT3 Protein, OCT4 Protein, OTF-3 Protein, OTF3 Protein, OTF4 Protein, Oct-3 Protein, Oct-4 Protein, POU5F1 Protein, gp9 Protein, gp-9 Protein, oct4 Protein, pou2 Protein, POU-2 Protein, cb197 Protein, spg/pou2 Protein, chunp6868 Protein, wu:fd18d06 Protein, NF-A3 Protein, Oct-3/4 Protein, Oct3 Protein, Oct3/4 Protein, Oct4 Protein, Otf-3 Protein, Otf-4 Protein, Otf3 Protein, Otf3-rs7 Protein, Otf3g Protein, Otf4 Protein, POU class 5 homeobox 1 Protein, POU domain, class 5, transcription factor 3 Protein, POU domain, class 5, transcription factor 1 Protein, POU5F1 Protein, pou5f3 Protein, Pou5f1 Protein
- 背景
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing&aposs sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
- 分子量
- 38.4 kDa
- NCBI登录号
- NP_002692
- 途径
- Stem Cell Maintenance
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