TR4 Protein (Myc-DYKDDDDK Tag)
-
- 抗原 See all TR4 (NR2C2) 蛋白
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This TR4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human NR2C2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR2C2 蛋白
-
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 别名
- Nr2c2 (NR2C2 产品)
- 别名
- TAK1 Protein, TR2R1 Protein, TR4 Protein, hTAK1 Protein, Tr4 Protein, gb:dq017625 Protein, im:6911408 Protein, mKIAA4145 Protein, nuclear receptor subfamily 2 group C member 2 Protein, nuclear receptor subfamily 2, group C, member 2 Protein, NR2C2 Protein, Nr2c2 Protein, nr2c2 Protein
- 背景
- This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- 67.2 kDa
- NCBI登录号
- NP_003289
- 途径
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
-