NARF Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
-
- 抗原 See all NARF 蛋白
- NARF (Nuclear Prelamin A Recognition Factor (NARF))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 3
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This NARF protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human NARF (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NARF 蛋白
-
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- NARF (Nuclear Prelamin A Recognition Factor (NARF))
- 别名
- Narf (NARF 产品)
- 别名
- NARF Protein, IOP2 Protein, 4430402O11Rik Protein, RGD1310894 Protein, wu:fa03c01 Protein, zgc:92186 Protein, nuclear prelamin A recognition factor Protein, nuclear prelamin A recognition factor L homeolog Protein, NARF Protein, NAEGRDRAFT_78871 Protein, VDBG_04882 Protein, Tsp_07547 Protein, Tsp_07549 Protein, Narf Protein, narf Protein, narf.L Protein
- 背景
- Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
- 分子量
- 44.5 kDa
- NCBI登录号
- NP_001033707
-