NACA Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- 抗原 See all NACA (NACa1) 蛋白
- NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 4
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NACA protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NACA (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NACa1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
- 别名
- Naca (NACa1 产品)
- 别名
- AL022831 Protein, AL024382 Protein, Gm1878 Protein, mKIAA0363 Protein, skNAC Protein, ik:tdsubc_2b5 Protein, nkn Protein, tdsubc_2b5 Protein, xx:tdsubc_2b5 Protein, NACA1 Protein, nascent polypeptide-associated complex alpha polypeptide Protein, nascent polypeptide-associated complex alpha subunit Protein, Naca Protein, naca Protein, NACA Protein
- 背景
- This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
- 分子量
- 23.2 kDa
- NCBI登录号
- NP_001106673
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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