MLH1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all MLH1 蛋白
- MLH1 (MutL Homolog 1 (MLH1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MLH1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human MLH1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MLH1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MLH1 (MutL Homolog 1 (MLH1))
- 别名
- Mlh1 (MLH1 产品)
- 别名
- CG11482 Protein, Dmel\\CG11482 Protein, dmlh-1 Protein, dmlh1 Protein, zgc:66301 Protein, MLH1 Protein, LOC100232198 Protein, 1110035C23Rik Protein, AI317206 Protein, AI325952 Protein, AI561766 Protein, COCA2 Protein, FCC2 Protein, HNPCC Protein, HNPCC2 Protein, hMLH1 Protein, mutL homolog 1 Protein, CG11482 gene product from transcript CG11482-RB Protein, mutL homolog 1 S homeolog Protein, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) Protein, DNA mismatch repair protein Mlh1 Protein, MLH1 Protein, Mlh1 Protein, mlh1.S Protein, mlh1 Protein, LOC588545 Protein
- 背景
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009].
- 分子量
- 84.4 kDa
- NCBI登录号
- NP_000240
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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