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JNK Protein (Myc-DYKDDDDK Tag)

MAPK8 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725440
发货至: 中国
  • 抗原 See all JNK (MAPK8) 蛋白
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    蛋白类型
    Recombinant
    宿主
    • 8
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    资源
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    HEK-293 Cells
    标记
    This JNK protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human MAPK8 / JNK1 (transcript variant JNK1-a1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MAPK8 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    别名
    Mapk8,jnk1 (MAPK8 产品)
    别名
    JNK Protein, JNK-46 Protein, JNK1 Protein, JNK1A2 Protein, JNK21B1/2 Protein, PRKM8 Protein, SAPK1 Protein, SAPK1c Protein, AI849689 Protein, Prkm8 Protein, BSK Protein, BSK/DJNK Protein, Bsk Protein, CG5680 Protein, D-JNK Protein, D-junk Protein, DBSK/JNK Protein, DJNK Protein, DJNK/bsk Protein, Dmel\\CG5680 Protein, JNK/SAPK Protein, Jnk Protein, Junk Protein, SAPKa Protein, c-Jun Protein, dJNK Protein, jnk Protein, T10F20.15 Protein, jnk1 Protein, sapk1 Protein, mapk8 Protein, zgc:112379 Protein, JNKb Protein, mapk8b Protein, mitogen-activated protein kinase 8 Protein, Stress-activated protein kinase jnk-1 Protein, basket Protein, Protein kinase superfamily protein Protein, mitogen-activated protein kinase 8 L homeolog Protein, mitogen-activated protein kinase 8b Protein, mitogen-activated protein kinase 8B-like Protein, MAPK8 Protein, jnk-1 Protein, Mapk8 Protein, bsk Protein, ATMPK8 Protein, mapk8.L Protein, mapk8b Protein, LOC109094263 Protein
    背景
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
    分子量
    44 kDa
    NCBI登录号
    NP_002741
    途径
    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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