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KLHL3 Protein (Myc-DYKDDDDK Tag)

KLHL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2724309
发货至: 中国
  • 抗原 See all KLHL3 蛋白
    KLHL3 (Kelch-Like 3 (KLHL3))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    HEK-293 Cells
    标记
    This KLHL3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human KLHL3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KLHL3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    KLHL3 (Kelch-Like 3 (KLHL3))
    别名
    Klhl3 (KLHL3 产品)
    别名
    7530408C15Rik Protein, AI430941 Protein, EG627648 Protein, PHA2D Protein, RGD1565218 Protein, kelch like family member 3 Protein, kelch-like 3 Protein, kelch-like family member 3 Protein, KLHL3 Protein, Klhl3 Protein
    背景
    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    分子量
    64.8 kDa
    NCBI登录号
    NP_059111
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