IDE Protein (Myc-DYKDDDDK Tag)
IDE
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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(1 reference)-
- 抗原 See all IDE 蛋白
- IDE (Insulin-Degrading Enzyme (IDE))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IDE protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Insulin-degrading enzyme protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IDE 蛋白
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Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (GST tag)
IDE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) (AA 920-1019) protein (GST tag)IDE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Analysis of the proteolysis of bioactive peptides using a peptidomics approach." in: Nature protocols, Vol. 8, Issue 9, pp. 1730-42, (2013) (PubMed).
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: "Analysis of the proteolysis of bioactive peptides using a peptidomics approach." in: Nature protocols, Vol. 8, Issue 9, pp. 1730-42, (2013) (PubMed).
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- 抗原
- IDE (Insulin-Degrading Enzyme (IDE))
- 别名
- Insulin-Degrading Enzyme (IDE 产品)
- 别名
- zgc:162603 Protein, IDE Protein, 1300012G03Rik Protein, 4833415K22Rik Protein, AA675336 Protein, AI507533 Protein, INSDEGM Protein, INSULYSIN Protein, insulin degrading enzyme Protein, insulin-degrading enzyme Protein, metallopeptidase Protein, IDE Protein, ide Protein, LOC591315 Protein, CC1G_01115 Protein, Bm1_26615 Protein, PTRG_10875 Protein, SJAG_01430 Protein, EBI_21700 Protein, VDBG_06702 Protein, LOAG_08082 Protein, PGTG_04982 Protein, Tsp_00424 Protein, Ide Protein
- 背景
- This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009].
- 分子量
- 117.8 kDa
- NCBI登录号
- NP_004960
- 途径
- SARS-CoV-2 Protein Interactome
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