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HERPUD1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

HERPUD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722961
发货至: 中国
  • 抗原 See all HERPUD1 蛋白
    HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 3
    宿主
    • 6
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This HERPUD1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 (HERPUD1), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HERPUD1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))
    Abstract
    HERPUD1 产品
    别名
    herpud1-a Protein, herp Protein, herpud1 Protein, mif1 Protein, sup Protein, HERPUD1 Protein, zgc:114134 Protein, HERP Protein, Mif1 Protein, SUP Protein, Herp Protein, Mifl Protein, Sup Protein, homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog Protein, homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog Protein, homocysteine inducible ER protein with ubiquitin like domain 1 Protein, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 Protein, herpud1.S Protein, herpud1.L Protein, herpud1 Protein, HERPUD1 Protein, Herpud1 Protein
    背景
    The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.
    分子量
    40.7 kDa
    NCBI登录号
    NP_001010990
    途径
    ER-Nucleus Signaling
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