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HAX1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

HAX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722446
发货至: 中国
  • 抗原 See all HAX1 蛋白
    HAX1 (HCLS1 Associated Protein X-1 (HAX1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This HAX1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human HAX1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HAX1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HAX1 (HCLS1 Associated Protein X-1 (HAX1))
    别名
    Hax1 (HAX1 产品)
    别名
    HAX1 Protein, hax1 Protein, HCLSBP1 Protein, HS1BP1 Protein, SCN3 Protein, HAX-1 Protein, Hs1bp1 Protein, HSP1BP-1 Protein, SIG-111 Protein, Silg111 Protein, mHAX-1s Protein, HCLS1 associated protein X-1 Protein, HCLS1 associated X-1 Protein, HAX1 Protein, hax1 Protein, Hax1 Protein
    背景
    The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    31.4 kDa
    NCBI登录号
    NP_006109
    途径
    Regulation of Actin Filament Polymerization
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