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GFRA1 Protein (Transcript Variant 3)

This Recombinant GFRA1 protein is expressed in HEK-293 Cells.
产品编号 ABIN2721853
发货至: 中国

Quick Overview for GFRA1 Protein (Transcript Variant 3) (ABIN2721853)

抗原

See all GFRA1 蛋白
GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

蛋白类型

Recombinant

宿主

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资源

  • 8
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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 3

    产品特性

    • Recombinant human GFRA1 / GDNFR-alpha (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone

    内毒素水平

    < 0.1 EU per μg protein as determined by LAL test
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    限制

    仅限研究用
  • 缓冲液

    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

    别名

    Gfra1,gdnfr-alpha

    背景

    This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

    分子量

    46.3 kDa

    NCBI登录号

    NP_001138925
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