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Fibulin 5 Protein (FBLN5) (Myc-DYKDDDDK Tag)

FBLN5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2721183
发货至: 中国
  • 抗原 See all Fibulin 5 (FBLN5) 蛋白
    Fibulin 5 (FBLN5)
    蛋白类型
    Recombinant
    宿主
    • 3
    • 3
    • 3
    • 1
    资源
    • 7
    • 2
    • 1
    HEK-293 Cells
    标记
    This Fibulin 5 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Fibulin-5 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FBLN5 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Sideek, Menz, Parsi, Gibson: "LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).

  • 抗原
    Fibulin 5 (FBLN5)
    别名
    Fibulin-5 (FBLN5 产品)
    别名
    zgc:103575 Protein, FBLN5 Protein, MGC108414 Protein, Fibulin-5 Protein, DKFZp469K0327 Protein, ADCL2 Protein, ARCL1A Protein, ARMD3 Protein, DANCE Protein, EVEC Protein, FIBL-5 Protein, UP50 Protein, A55 Protein, fibulin 5 Protein, fbln5 Protein, FBLN5 Protein, Fbln5 Protein
    背景
    The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
    分子量
    47.8 kDa
    NCBI登录号
    NP_006320
    途径
    SARS-CoV-2 Protein Interactome
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