PTK2B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all PTK2B 蛋白
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PTK2B protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human FAK2 / PTK2B (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTK2B 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 别名
- Fak2,ptk2b (PTK2B 产品)
- 别名
- CADTK Protein, CAKB Protein, FADK2 Protein, FAK2 Protein, PKB Protein, PTK Protein, PYK2 Protein, RAFTK Protein, CAKbeta Protein, E430023O05Rik Protein, Raftk Protein, Pyk2 Protein, fak1b Protein, ptk2.2 Protein, ptk2b Protein, si:ch1073-355e8.1 Protein, protein tyrosine kinase 2 beta Protein, PTK2 protein tyrosine kinase 2 beta Protein, protein tyrosine kinase 2aa Protein, PTK2B Protein, Ptk2b Protein, ptk2aa Protein
- 背景
- This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
- 分子量
- 115.7 kDa
- NCBI登录号
- NP_004094
- 途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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