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BCL2A1 Protein (Transcript Variant 2)

BCL2A1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715200
发货至: 中国
  • 抗原 See all BCL2A1 蛋白
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 6
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Bcl-2-like 5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product BCL2A1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 10 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    别名
    Bcl-2-Like 5 (BCL2A1 产品)
    别名
    ACC-1 Protein, ACC-2 Protein, BCL2L5 Protein, BFL1 Protein, GRS Protein, HBPA1 Protein, Bcl2a1d Protein, BCL2A1 Protein, BCL2 related protein A1 Protein, BCL2-related protein A1 Protein, BCL2A1 Protein, Bcl2a1 Protein
    背景
    This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    18.5 kDa
    NCBI登录号
    NP_001108207
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