BCL2A1 Protein (Transcript Variant 2)
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- 抗原 See all BCL2A1 蛋白
- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Bcl-2-like 5 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product BCL2A1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 10 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
- 别名
- Bcl-2-Like 5 (BCL2A1 产品)
- 背景
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 18.5 kDa
- NCBI登录号
- NP_001108207
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