Apoptosis Inhibitor 5 Protein (API5) (Transcript Variant 3) (Myc-DYKDDDDK Tag)
-
- 抗原 See all Apoptosis Inhibitor 5 (API5) 蛋白
- Apoptosis Inhibitor 5 (API5)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 3
- 宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Apoptosis Inhibitor 5 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human API5 / MIG8 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product API5 蛋白
-
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- Apoptosis Inhibitor 5 (API5)
- 别名
- Api5,mig8 (API5 产品)
- 别名
- AAC-11 Protein, AAC11 Protein, AI196452 Protein, api5l1 Protein, sr:nyz021 Protein, zgc:66211 Protein, wu:fb26c03 Protein, API-5B Protein, aac-11 Protein, aac11 Protein, api5 Protein, API-5A Protein, api5-A Protein, MGC83290 Protein, API5 Protein, apoptosis inhibitor 5 Protein, apoptosis inhibitor 5 S homeolog Protein, apoptosis inhibitor 5 L homeolog Protein, API5 Protein, Api5 Protein, api5 Protein, api5.S Protein, api5.L Protein
- 背景
- This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- 分子量
- 50.6 kDa
- NCBI登录号
- NP_001136403
- 途径
- Growth Factor Binding
-