PRKAB2 Protein (His tag)
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- 抗原 See all PRKAB2 蛋白
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PRKAB2 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human AMPK beta-2 chain / PRKAB2 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAB2 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- 别名
- Ampk beta-2 Chain,prkab2 (PRKAB2 产品)
- 别名
- prkab2 Protein, MGC64365 Protein, PRKAB2 Protein, DKFZp469M1118 Protein, 5730553K21Rik Protein, AW049591 Protein, BB124140 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog Protein, protein kinase AMP-activated non-catalytic subunit beta 2 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit Protein, prkab2.L Protein, PRKAB2 Protein, prkab2 Protein, Prkab2 Protein
- 背景
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
- 分子量
- 30.1 kDa
- NCBI登录号
- NP_005390
- 途径
- AMPK Signaling, Warburg Effect
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