CDC42 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all CDC42 蛋白
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CDC42 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CDC42 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CDC42 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 别名
- Cdc42 (CDC42 产品)
- 别名
- CDC42Hs Protein, G25K Protein, AI747189 Protein, AU018915 Protein, cdc42a Protein, wu:fb07d08 Protein, wu:fj62g06 Protein, zgc:63918 Protein, Xcdc42 Protein, cdc42hs Protein, g25k Protein, CDC42 Protein, CG12530 Protein, Cdc42Dm Protein, D-CDC42 Protein, D-Cdc42 Protein, D-cdc42 Protein, DCDC42 Protein, DCdc42 Protein, Dcdc42 Protein, Dm Cdc42 Protein, DmCDC42 Protein, Dmcdc42 Protein, Dmel\\CG12530 Protein, cdc42 Protein, cell division cycle 42 Protein, Cell division control protein 42 homolog Protein, cell division control protein 42 homolog Protein, cell division cycle 42 L homeolog Protein, CG12530 gene product from transcript CG12530-RC Protein, Rho family GTPase Protein, CDC42 Protein, Cdc42 Protein, cdc42 Protein, LOC100636735 Protein, LOC100637699 Protein, LOC100638834 Protein, cdc42.L Protein
- 背景
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
- 分子量
- 21.1 kDa
- NCBI登录号
- NP_001782
- 途径
- MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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