CD3 Protein (CD3) (Myc-DYKDDDDK Tag)
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- 抗原 See all CD3 蛋白
- CD3
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD3 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CD3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CD3
- 别名
- CD3 (CD3 产品)
- 别名
- CD3 Protein, AI504783 Protein, CD3epsilon Protein, T3e Protein, cd3-gamma Protein, cd3g Protein, cd3g-a Protein, cd3g/d Protein, cd3gd Protein, t3g Protein, CD3e molecule Protein, CD3d molecule Protein, CD3 antigen, epsilon polypeptide Protein, CD3g molecule S homeolog Protein, CD3E Protein, CD3D Protein, Cd3e Protein, cd3g.S Protein
- 背景
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
- 分子量
- 20.7 kDa
- NCBI登录号
- NP_000724
- 途径
- TCR Signaling, Ubiquitin Proteasome Pathway
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