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Calpain 6 Protein (CAPN6) (Myc-DYKDDDDK Tag)

CAPN6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713062
发货至: 中国
  • 抗原 See all Calpain 6 (CAPN6) 蛋白
    Calpain 6 (CAPN6)
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This Calpain 6 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Calpain-6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CAPN6 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Calpain 6 (CAPN6)
    别名
    Calpain-6 (CAPN6 产品)
    别名
    CAPN6 Protein, CANPX Protein, CAPNX Protein, CalpM Protein, DJ914P14.1 Protein, calpain 6 Protein, CAPN6 Protein, Capn6 Protein
    背景
    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
    分子量
    74.4 kDa
    NCBI登录号
    NP_055104
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