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Factor VII Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

F7 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712925
发货至: 中国
  • 抗原 See all Factor VII (F7) 蛋白
    Factor VII (F7) (Coagulation Factor VII (F7))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    资源
    • 9
    • 5
    • 2
    • 2
    HEK-293 Cells
    标记
    This Factor VII protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Coagulation factor VII (F7) (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product F7 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Factor VII (F7) (Coagulation Factor VII (F7))
    Abstract
    F7 产品
    别名
    F7 Protein, wu:fb59f04 Protein, zgc:109870 Protein, SPCA Protein, AI114908 Protein, ATIII Protein, At-3 Protein, At3 Protein, LOC100223776 Protein, AI132620 Protein, Cf7 Protein, FVII Protein, mfVII Protein, f7 Protein, coagulation factor VII Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog Protein, F7 Protein, f7 Protein, Serpinc1 Protein, CpipJ_CPIJ009142 Protein, CpipJ_CPIJ010295 Protein, CpipJ_CPIJ020127 Protein, fa7 Protein, f7.S Protein
    背景
    This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
    分子量
    28 kDa
    NCBI登录号
    NP_062562
    途径
    Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
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