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Cyclin D1 Protein (CCND1) (DYKDDDDK Tag)

CCND1 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712724
发货至: 中国
  • 抗原 See all Cyclin D1 (CCND1) 蛋白
    Cyclin D1 (CCND1)
    蛋白类型
    Recombinant
    宿主
    • 10
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    资源
    • 14
    • 5
    • 2
    • 1
    • 1
    Insect cells (Sf9)
    标记
    This Cyclin D1 protein is labelled with DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Cyclin D1 (full length, C-term flag tag) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CCND1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 7 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Cyclin D1 (CCND1)
    别名
    Cyclin d1 (CCND1 产品)
    别名
    BCL1 Protein, D11S287E Protein, PRAD1 Protein, U21B31 Protein, AI327039 Protein, CycD1 Protein, Cyl-1 Protein, bcl-1 Protein, cD1 Protein, cb161 Protein, cycd1 Protein, etID37810.7 Protein, fb52e01 Protein, fc45c08 Protein, fc83a12 Protein, id:ibd1198 Protein, wu:fb52e01 Protein, wu:fc45c08 Protein, wu:fc83a12 Protein, ccnd1b Protein, prad1 Protein, ccnd1 Protein, ccnd1a Protein, bcl1 Protein, d11s287e Protein, u21b31 Protein, CCND1 Protein, cyclin D1 Protein, cyclin D1 S homeolog Protein, cyclin D1 L homeolog Protein, CCND1 Protein, Ccnd1 Protein, ccnd1 Protein, ccnd1.S Protein, ccnd1.L Protein
    背景
    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
    分子量
    34 kDa
    NCBI登录号
    NP_444284
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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