Crk Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all Crk (CRK) 蛋白
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Crk protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CRK (transcript variant II) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CRK 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- 别名
- Crk (CRK 产品)
- 别名
- CG1587 Protein, CRK Protein, D-CRK Protein, D-Crk Protein, DCrk Protein, Dcrk Protein, Dmel\\CG1587 Protein, crk Protein, dCRK Protein, dCrk Protein, fb34h10 Protein, fc05a01 Protein, fi19g05 Protein, wu:fb34h10 Protein, wu:fc05a01 Protein, wu:fc54a04 Protein, wu:fi19g05 Protein, zgc:100936 Protein, CRKII Protein, p38 Protein, Crko Protein, crk2 Protein, crkII Protein, v-crk Protein, P38C-CRK Protein, Crk-I Protein, Crk-II Protein, Crk-III Protein, Crk3 Protein, CrkIII Protein, c-Crk Protein, Crk oncogene Protein, v-crk avian sarcoma virus CT10 oncogene homolog Protein, CRK proto-oncogene, adaptor protein Protein, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog Protein, v-crk sarcoma virus CT10 oncogene homolog Protein, Crk Protein, crk Protein, CRK Protein, crk.L Protein
- 背景
- This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
- 分子量
- 33.7 kDa
- NCBI登录号
- NP_058431
- 途径
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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