FGF10 Protein (AA 40-208, N-Term)
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- 抗原 See all FGF10 蛋白
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 40-208, N-Term
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Flow Cytometry (FACS)
- 纯度
- >95 % , as determined by Coomassie stained SDS-PAGE gel and HLPC analysis.
- 内毒素水平
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Less than 0.1 ng per μg of protein.
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) protein (Biotin)
FGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 10 (FGF10) proteinFGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% as determined by Tris-Bis PAGE
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His tag)FGF10 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Biological activity: ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106 units/mg, as measured by its ability to stimulate thymidine uptake by BaF3 cells expressing FGF receptors in a dose dependent manner.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- For maximum results, quick spin vial prior to opening. Reconstitute in 5 mM sodium phosphate, pH 8.0 to a concentration of <0.5 mg/mL. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.
- 缓冲液
- Lyophilized, carrier-free.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Unopened vial can be stored at -20°C or -70°C.
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- 抗原
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- 别名
- FGF-10 (FGF10 产品)
- 别名
- fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
- 背景
- FGF-10, also named keratinocyte growth factor 2 (KGF-2), is a member of the fibroblast growth factor (FGF) family and is functionally similar to the other FGF family member FGF-7. FGF-10 acts as a paracrine growth factor and plays an important role in embryonic development, cell growth, and cell differentiation. During embryonic stages, FGF-10 is essential for lung development, promoting lung morphogenesis, branching, and airway extension. FGF-10 was revealed to participate in wound healing, promoting growth of epithelial cells in normal and wounded tissue. Increased expression of FGF-10 and the receptor FGFR2-IIIb has been reported to associate with various malignant diseases, such as prostate, breast, pancreas, and colorectum cancer, suggesting the role of FGF-10 in carcinogenesis.
- 分子量
- The 170 amino acid recombinant protein has a predicted molecular mass of approximately 19.3 kDa. The predicted N-terminal amino acid is Met.
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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