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CXCL17 Protein (AA 23-119)

CXCL17 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % , as determined by Coomassie stained SDS-PAGE. ELISA Active
产品编号 ABIN2666919
发货至: 中国
  • 抗原 See all CXCL17 蛋白
    CXCL17 (Chemokine (C-X-C Motif) Ligand 17 (CXCL17))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-119
    宿主
    • 4
    • 4
    • 3
    • 1
    • 1
    小鼠
    资源
    • 12
    • 1
    大肠杆菌(E. Coli)
    应用范围
    ELISA
    纯度
    > 98 % , as determined by Coomassie stained SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平

    Less than 0.01 ng per μg cytokine as determined by the LAL method.

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    Discover our top product CXCL17 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Biological activity: Bioactivity was measured by its antimicrobial activity (E.coli) in a dose dependent manner.

    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10 μg/mL in sterile buffer (PBS, HPBS, DPBS, and EBSS) containing carrier protein such as 1 % BSA or HSA. After dilution, the cytokine can be stored between 2 °C and 8 °C for one month or from -20 °C to -70 °C for up to 3 months.
    缓冲液
    0.22 μm filtered protein solution is in PBS.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Unopened vial can be stored between 2°C and 8°C for three months, at -20°C for six months, or at -70°C for one year.
  • 抗原
    CXCL17 (Chemokine (C-X-C Motif) Ligand 17 (CXCL17))
    别名
    CXCL17 (CXCL17 产品)
    别名
    DMC Protein, Dcip1 Protein, UNQ473 Protein, VCC-1 Protein, VCC1 Protein, Vcc1 Protein, RGD1304717 Protein, C-X-C motif chemokine ligand 17 Protein, chemokine (C-X-C motif) ligand 17 Protein, CXCL17 Protein, Cxcl17 Protein
    背景
    CXCL17 is the latest identified member of the CXC chemokine family and may contribute to tumor angiogenesis and progression. Ectopic expression of human CXCL17 in HUVEC significantly upregulated the RNA level of genes involved in angiogenesis including VEGF-A and basic FGF. NIH3T3 cells overexpressing human or mouse CXCL17 developed rapid growing tumors in mice. In vitro chemotaxis assay shows that human CXCL17 can induce migration of CD14+ monocytes and CD11c+ immature dendritic cells from human peripheral blood, and mouse CXCL17 can induce CD11b+Gr1highF4/80- cells from mouse spleen cells. CXCL17 also shows broad antimicrobial activity by disrupting bacterial membrane. High levels of CXCL17 have been detected in bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis.
    分子量
    The 97 amino acid recombinant protein has a predicted molecular mass of approximately 10.3 kDa. The DTT-reduced protein migrates at approximately 10 kDa and non-reduced protein migrates at approximately 18 kDa by SDS-PAGE. The N-terminal amino acid is Ser
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