CXCL17 Protein (AA 24-119)
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- 抗原 See all CXCL17 蛋白
- CXCL17 (Chemokine (C-X-C Motif) Ligand 17 (CXCL17))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-119
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Flow Cytometry (FACS)
- 纯度
- > 98 % , as determined by Coomassie stained SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
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Less than 0.01 ng per μg cytokine as determined by the LAL method.
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Chemokine (C-X-C Motif) Ligand 17 (CXCL17) (AA 22-119) protein (His tag)
CXCL17 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Chemokine (C-X-C Motif) Ligand 17 (CXCL17) (AA 23-119) protein (His tag)CXCL17 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Biological activity: Bioactivity was measured by its antimicrobial activity (E.coli) in a dose dependent manner.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10 μg/mL in sterile buffer (PBS, HPBS, DPBS, and EBSS) containing carrier protein such as 1 % BSA or HSA. After dilution, the cytokine can be stored between 2 °C and 8 °C for one month or from -20 °C to -70 °C for up to 3 months.
- 缓冲液
- 0.22 μm filtered protein solution is in PBS.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Unopened vial can be stored between 2°C and 8°C for three months, at -20°C for six months, or at -70°C for one year.
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- 抗原
- CXCL17 (Chemokine (C-X-C Motif) Ligand 17 (CXCL17))
- 别名
- CXCL17 (CXCL17 产品)
- 别名
- DMC Protein, Dcip1 Protein, UNQ473 Protein, VCC-1 Protein, VCC1 Protein, Vcc1 Protein, RGD1304717 Protein, C-X-C motif chemokine ligand 17 Protein, chemokine (C-X-C motif) ligand 17 Protein, CXCL17 Protein, Cxcl17 Protein
- 背景
- CXCL17 is the latest identified member of the CXC chemokine family and may contribute to tumor angiogenesis and progression. Ectopic expression of human CXCL17 in HUVEC significantly upregulated the RNA level of genes involved in angiogenesis including VEGF-A and basic FGF. NIH3T3 cells overexpressing human or mouse CXCL17 developed rapid growing tumors in mice. In vitro chemotaxis assay shows that human CXCL17 can induce migration of CD14+ monocytes and CD11c+ immature dendritic cells from human peripheral blood, and mouse CXCL17 can induce CD11b+Gr1highF4/80- cells from mouse spleen cells. CXCL17 also shows broad antimicrobial activity by disrupting bacterial membrane. High levels of CXCL17 have been detected in bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis.
- 分子量
- The 96 amino acid recombinant protein has a predicted molecular mass of approximately 11.3 kDa. The DTT-reduced protein migrates at approximately 11.3 kDa and non-reduced protein migrates at approximately 24 kDa by SDS-PAGE. The N-terminal amino acid is L
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