CXCL11 Protein (AA 22-100)
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- 抗原 See all CXCL11 蛋白
- CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-100
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Multiplex Assay (MA)
- 纯度
- > 98 % , as determined by Coomassie stained SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
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Less than 0.01 ng per μg cytokine as determined by the LAL method.
- Top Product
- Discover our top product CXCL11 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Biological activity: Bioactivity was measured by its property to chemoattract Baf3-hCXCR3 transfectants in a dose dependent manner.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- For maximum results, quick spin vial prior to opening. The protein can be aliquoted and stored from -20 °C to -70 °C. Stock solutions can also be prepared at 50-100 μg/mL in sterile buffer (PBS, HPBS, DPBS, or EBSS) containing carrier protein such as 0.2-1 % BSA or HSA and stored in working aliquots at -20 °C to -70 °C.
- 缓冲液
- 0.22 μm filtered protein solution is in PBS.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Unopened vial can be stored between 2°C and 8°C for one month, at -20°C for six months, or at -70°C for one year.
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- 抗原
- CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))
- 别名
- CXCL11 (CXCL11 产品)
- 别名
- H174 Protein, I-TAC Protein, IP-9 Protein, IP9 Protein, SCYB11 Protein, SCYB9B Protein, b-R1 Protein, Cxc11 Protein, I-tac Protein, Ip9 Protein, Itac Protein, Scyb11 Protein, Scyb9b Protein, betaR1 Protein, C-X-C motif chemokine ligand 11 Protein, chemokine (C-X-C motif) ligand 11 Protein, CXCL11 Protein, Cxcl11 Protein
- 背景
- CXCL11 is a CXC chemokine lacking the ELR (Glutamate-Leucine-Arginine) tripeptide motif, which is functionally and structurally related to CXCL9 and CXCL10. CXCL11, together with CXCL9 and CXCL10, specifically binds to the G protein-coupled receptor CXCR3 and is involved in chemotaxis of immune cells and angiogenesis. Expression of both CXCR3 and CXCL11 by the Th1-associated cytokine IFNγ creates an amplification loop of cell-mediated immune response between Th1 cells. CXCR7 has been identified as an alternate receptor for CXCL11 and is involved in growth, survival, and adhesion of tumor cells.
- 分子量
- The 80 amino acid recombinant protein has a predicted molecular mass of approximately 9.1 kDa. The DTT-reduced protein migrates at approximately 11 kDa and non-reduced protein migrates at approximately 13 kDa by SDS-PAGE. The N-terminal amino acid is Meth
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