Protein A 蛋白
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- 抗原 See all Protein A 蛋白
- Protein A
- 蛋白类型
- Native
- 宿主
- Staphylococcus aureus
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资源
- Staphylococcus aureus
- 产品特性
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Immunoglobulin-binding bacterial Protein A solution
Protein Source: Staphylococcus aureus - 纯度
- > 95 % pure
- Top Product
- Discover our top product Protein A 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and store at -20 °C.
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- 抗原
- Protein A
- Abstract
- Protein A 产品
- 背景
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Protein A is a 40-60 kDa MSCRAMM surface protein originally found in the cell wall of the bacteria Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It binds proteins from many of mammalian species, most notably IgGs. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. The result of this type of interaction is that, in serum, the bacteria will bind IgG molecules in the wrong orientation (in relation to normal antibody function) on their surface which disrupts opsonization and phagocytosis.
Description: Staphylococcus aureus.
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