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Protein A 蛋白

宿主: Staphylococcus aureus 宿主: Staphylococcus aureus Native > 95 % pure
产品编号 ABIN2648105
发货至: 中国
  • 抗原 See all Protein A 蛋白
    Protein A
    蛋白类型
    Native
    宿主
    Staphylococcus aureus
    资源
    • 8
    • 1
    Staphylococcus aureus
    产品特性
    Immunoglobulin-binding bacterial Protein A solution
    Protein Source: Staphylococcus aureus
    纯度
    > 95 % pure
    Top Product
    Discover our top product Protein A 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C.
  • 抗原
    Protein A
    Abstract
    Protein A 产品
    背景
    Protein A is a 40-60 kDa MSCRAMM surface protein originally found in the cell wall of the bacteria Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It binds proteins from many of mammalian species, most notably IgGs. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. The result of this type of interaction is that, in serum, the bacteria will bind IgG molecules in the wrong orientation (in relation to normal antibody function) on their surface which disrupts opsonization and phagocytosis.
    Description: Staphylococcus aureus.
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