IL-24 蛋白
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- 抗原 See all IL-24 (IL24) 蛋白
- IL-24 (IL24) (Interleukin 24 (IL24))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- CHO Cells
- 序列
- QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
- 纯度
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Top Product
- Discover our top product IL24 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- IL-24 (IL24) (Interleukin 24 (IL24))
- 别名
- IL-24 (IL24 产品)
- 背景
- IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
- 基因ID
- 11009
- NCBI登录号
- NP_001172085
- OMIM
- 297632401
- UniProt
- Q13007
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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